UCSF's Center for Intelligent Imaging (ci2)'s Rupsa Bhattacharjee, PhD, represented UC San Francisco in June at the 2023 International Society for Magnetic Resonance in Medicine (ISMRM) annual meeting. Dr. Bhattacharjee presented a digital poster and a power pitch. The poster was selected by reviewers as one of the top musculoskeletal abstracts and has been invited for a full manuscript write-up at JMRI journal. Both of the abstracts were awarded Summa-cum-Laude and were scored among the top 5% within the major subject review category.
The digital poster, "Preserved patellar cartilage at the expense of anterior femoral cartilage damage in hip osteoarthritis: An inter-limb inter-joint qMRI analysis," was first-authored by Dr. Bhattacharjee. ci2's Sharmila Majumdar, PhD, is the corresponding author, and additional authors include Johanna Luitjens, MD, Misung Han, PhD, Rafeek Thahakoya, PhD, Koren Roach, PhD, and Valentina Pedoia, PhD, of the UCSF Department of Radiology and Biomedical Imaging, and Richard Souza, PhD, of UCSF Radiology and the UCSF Department of Physical Therapy and Rehabilitation Science.
The study looks at the novel relationship between compositional biomarkers of the bilateral hip cartilage and contralateral patellofemoral cartilage in a mixed population of hip osteoarthritis as well as normal subjects to shed light on the effect of hip characteristic T1rho changes on the knee T1rho.
"These findings [may] eventually lead to a better understanding of cross-talks between the two joints and might be useful for predicting disease progression and/or prevention of the overall joint health," write Dr. Bhattacharjee et al.
The power pitch, "Towards the understanding of the role of functional strength markers in cartilage-bone cross talk: A PET/MRI study in isolated PFJOA patients," was also led by Dr. Bhattacharjee. Dr. Pedoia is the corresponding author, and additional authors include Dr. Roach, Dr. Souza and Dr. Majumdar, as well as UCSF Radiology's Emma Bahroos and UCSF Physical Therapy's Eric Hammond.
The authors present "one of the first studies to explore bone remodeling in isolated [patellofemoral-joint osteoarthritis (PFJOA)] in correlation with knee isometric strength and cartilage compartmental T1rho," write Dr. Bhattacharjee et al.
Read more about research and news at UCSF ci2.
