Spencer Behr, MD

Associate Professor
Radiology
+1 415 353-4889

Spencer Behr, MD, is an Associate Professor of Clinical Radiology and the Director of the Fellowship for both the Abdominal Imaging subspecialty and for the Department of Radiology and Biomedical Imaging at the University of California, San Francisco. He obtained his medical degree from Tufts University School of Medicine, Boston in 2005. In 2010, he completed a four-year Diagnostic Radiology residency at the Lahey Clinic Medical Center in Burlington, Massachusetts, followed by a fellowship in Abdominal Imaging and Nuclear Medicine at UCSF.

Dr. Behr has subspecialty training in abdominal imaging and nuclear medicine, and his research interests are focused on molecular and hybrid imaging translational research. He has selectively pursued interdepartmental projects to foster cross-disciplinary discussions and optimize the clinical impact of these projects.

Projects include: FDG PET in breast cancer, comparing breast cancer molecular subtypes with their respective FDG PET and breast MRI findings, CT findings in Celiac Disease, fluoro-18-fluorothymidine (FLT) PET as a potential marker of early response in patients with metastatic melanoma, CT appearance of malabsorption, and clinical applications of iodine-124 PET/CT in thyroid cancer.

Expertise:
Abdominal Imaging and Nuclear Medicine

Specialty:
Molecular and hybrid imaging translational research

Professional Interests:
Translational research in the fields of prostate and the development of novel imaging techniques using PET/CT and PET/MR

Education and Training:
• Medical School: Tufts University School of Medicine, Boston - Medicine
• Internship: Saint Vincent Hospital, Worchester - Medicine
• Residency: Lahey Clinic Medical Center, Burlington - Diagnostic Radiology
• Residency: Lahey Clinic Medical Center, Burlington - Chief Resident, Diagnostic Radiology
• Fellowship: University of California, San Francisco - Abdominal Imaging
• Fellowship: University of California, San Francisco - Nuclear Medicine
• American Board of Nuclear Medicine
• American Board of Radiology with Authorized User - Board Certified 2010
• Full Medical License: California
• ACLS, BLS Certification
• Fluoroscopy License

Publications: 

Use of advanced PET-volume metrics predicts risk of local recurrence and overall survival in anal cancer.

PloS one

Susko MS, Lazar AA, Wang CJ, Van Loon K, Feng M, Hope TA, Behr S, Anwar M

Quantitative Assessment of Myocardial Ischemia With Positron Emission Tomography.

Journal of thoracic imaging

Sohn JH, Behr SC, Hernandez Pampaloni M, Seo Y

Association of image-defined risk factors with clinical features, histopathology, and outcomes in neuroblastoma.

Cancer medicine

Temple WC, Vo KT, Matthay KK, Balliu B, Coleman C, Michlitsch J, Phelps A, Behr S, Zapala MA

Education of prostate MR imaging: commentary.

Abdominal radiology (New York)

Merritt BA, Behr SC

Recent updates and developments in PET imaging of prostate cancer.

Abdominal radiology (New York)

Rowe SP, Johnson GB, Pomper MG, Gorin MA, Behr SC

Visceral Aneurysm Formation and Intraabdominal Hemorrhage Associated with Immune Checkpoint Inhibitor Therapy.

Journal of vascular and interventional radiology : JVIR

Lee AY, Lam A, Hicks RB, Isikbay M, Heller MB, Sugi MD, Behr S, Kohi MP

Gastrointestinal Stromal Tumor Incidentally Detected on 18F-Fluciclovine PET/CT.

Clinical nuclear medicine

Raghavan K, Flavell RR, Westphalen AC, Behr SC

Molecular Insights in Transmission of Cancer From an Organ Donor to Four Transplant Recipients.

Journal of the National Comprehensive Cancer Network : JNCCN

Atreya CE, Collisson EA, Park M, Grenert JP, Behr SC, Gonzalez A, Chou J, Maisel S, Friedlander TW, Freise CE, Shoji J, Semrad TJ, Van Ziffle J, Chin-Hong P

Gallium-68 prostate-specific membrane antigen ([68Ga]Ga-PSMA-11) PET for imaging of thyroid cancer: a feasibility study.

EJNMMI research

Lawhn-Heath C, Yom SS, Liu C, Villanueva-Meyer JE, Aslam M, Smith R, Narwal M, Juarez R, Behr SC, Pampaloni MH, Chan JW, Glastonbury CM, Hope TA, Flavell RR

The synthesis and structural requirements for measuring glucocorticoid receptor expression in vivo with (±)-11C-YJH08 PET.

Journal of nuclear medicine : official publication, Society of Nuclear Medicine

Huang Y, Zhao N, Wang YH, Truillet C, Wei J, Parker MFL, Blecha JE, Drake CR, VanBrocklin HF, Ruiz DG, Jacobson MP, Aggarwal R, Behr SC, Flavell RR, Wilson DM, Seo Y, Evans MJ

Hybrid Low-Grade Fibromyxoid Sarcoma and Sclerosing Epithelioid Fibrosarcoma of the Pancreas.

Journal of gastrointestinal cancer

Kramer SP, Bowman CJ, Wang ZJ, Sheahon KM, Nakakura EK, Cho SJ, Umetsu SE, Behr SC

Impact of 68Ga-PSMA-11 PET on the Management of recurrent Prostate Cancer in a Prospective Single-Arm Clinical Trial.

Journal of nuclear medicine : official publication, Society of Nuclear Medicine

Fendler WP, Ferdinandus J, Czernin J, Eiber M, Flavell RR, Behr SC, Wu IK, Lawhn-Heath C, Pampaloni MH, Reiter RE, Rettig MB, Gartmann J, Murthy V, Slavik R, Carroll PR, Herrmann K, Calais J, Hope TA

Factors predicting metastatic disease in 68Ga-PSMA-11 PET positive osseous lesions in prostate cancer.

Journal of nuclear medicine : official publication, Society of Nuclear Medicine

Chiu LW, Lawhn-Heath C, Behr S, Juarez R, Perez PM, Lobach I, Bucknor MD, Hope TA, Flavell RR

A novel radioligand reveals tissue specific pharmacological modulation of glucocorticoid receptor expression with positron emission tomography.

ACS chemical biology

Huang Y, Zhao N, Wang YH, Truillet C, Wei J, Blecha JE, VanBrocklin HF, Seo Y, Sayeed M, Feldman BJ, Aggarwal R, Behr SC, Shao H, Wilson DM, Villanueva-Meyer JE, Gestwicki JE, Evans MJ

Quantitative and Qualitative Improvement of Low-Count [68Ga]Citrate and [90Y]Microspheres PET Image Reconstructions Using Block Sequential Regularized Expectation Maximization Algorithm.

Molecular imaging and biology

Seo Y, Khalighi MM, Wangerin KA, Deller TW, Wang YH, Jivan S, Kohi MP, Aggarwal R, Flavell RR, Behr SC, Evans MJ

18F-Labeled, PSMA-Targeted Radiotracers: Leveraging the Advantages of Radiofluorination for Prostate Cancer Molecular Imaging.

Theranostics

Werner RA, Derlin T, Lapa C, Sheikbahaei S, Higuchi T, Giesel FL, Behr S, Drzezga A, Kimura H, Buck AK, Bengel FM, Pomper MG, Gorin MA, Rowe SP

Imaging of Infertility, Part 2: Hysterosalpingograms to Magnetic Resonance Imaging.

Radiologic clinics of North America

Merritt BA, Behr SC, Khati NJ

Imaging of Infertility, Part 1: Hysterosalpingograms to Magnetic Resonance Imaging.

Radiologic clinics of North America

Merritt BA, Behr SC, Khati NJ

Anastomosing hemangioma of liver.

Journal of radiology case reports

Merritt B, Behr S, Umetsu SE, Roberts J, Kolli KP

Single-Center Prospective Evaluation of 68Ga-PSMA-11 PET in Biochemical Recurrence of Prostate Cancer.

AJR. American journal of roentgenology

Lawhn-Heath C, Flavell RR, Behr SC, Yohannan T, Greene KL, Feng F, Carroll PR, Hope TA

Comparison of Positive Oral Contrast Agents for Abdominopelvic CT.

AJR. American journal of roentgenology

Winklhofer S, Lin WC, Wang ZJ, Behr SC, Westphalen AC, Yeh BM

Heterogeneous Uptake of 18F-FDG and 68Ga-PSMA-11 in Hepatocellular Carcinoma.

Clinical nuclear medicine

Perez PM, Flavell RR, Kelley RK, Umetsu S, Behr SC

Distinguishing Tumor From Bland Portal Vein Thrombus in Liver Transplant Candidates With Hepatocellular Carcinoma: the A-VENA Criteria.

Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society

Sherman CB, Behr S, Dodge JL, Roberts JP, Yao FY, Mehta N

Genomic Risk Predicts Molecular Imaging-detected Metastatic Nodal Disease in Prostate Cancer.

European urology oncology

Xu MJ, Kornberg Z, Gadzinski AJ, Diao D, Cowan JE, Wu SY, Boreta L, Spratt DE, Behr SC, Nguyen HG, Cooperberg MR, Davicioni E, Roach M, Hope TA, Carroll PR, Feng FY

Intertumoral Heterogeneity of 18F-FDG and 68Ga-PSMA Uptake in Prostate Cancer Pulmonary Metastases.

Clinical nuclear medicine

Perez PM, Hope TA, Behr SC, van Zante A, Small EJ, Flavell RR

First-in-Human Phase I study of CTT1057, a Novel 18F Labeled Imaging Agent with Phosphoramidate Core Targeting Prostate Specific Membrane Antigen in Prostate Cancer.

Journal of nuclear medicine : official publication, Society of Nuclear Medicine

Behr SC, Aggarwal R, Van Brocklin HF, Flavell RR, Geo K, Small EJ, Blecha J, Jivan S, Hope TA, Simko JP, Kurhanewicz J, Noworolski SM, Korn NJ, De Los Santos R, Cooperberg MR, Carroll PR, Nguyen HG, Greene KL, Langton-Webster B, Berkman CE, Seo Y

A Deep Learning Model to Predict a Diagnosis of Alzheimer Disease by Using 18F-FDG PET of the Brain.

Radiology

Ding Y, Sohn JH, Kawczynski MG, Trivedi H, Harnish R, Jenkins NW, Lituiev D, Copeland TP, Aboian MS, Mari Aparici C, Behr SC, Flavell RR, Huang SY, Zalocusky KA, Nardo L, Seo Y, Hawkins RA, Hernandez Pampaloni M, Hadley D, Franc BL

Targeting iron metabolism in high-grade glioma with 68Ga-citrate PET/MR.

JCI insight

Behr SC, Villanueva-Meyer JE, Li Y, Wang YH, Wei J, Moroz A, Lee JK, Hsiao JC, Gao KT, Ma W, Cha S, Wilson DM, Seo Y, Nelson SJ, Chang SM, Evans MJ

Exploration of PET and MRI radiomic features for decoding breast cancer phenotypes and prognosis.

NPJ breast cancer

Huang SY, Franc BL, Harnish RJ, Liu G, Mitra D, Copeland TP, Arasu VA, Kornak J, Jones EF, Behr SC, Hylton NM, Price ER, Esserman L, Seo Y

Early Response Assessment in Pancreatic Ductal Adenocarcinoma Through Integrated PET/MRI.

AJR. American journal of roentgenology

Wang ZJ, Behr S, Consunji MV, Yeh BM, Ohliger MA, Gao K, Ko AH, Cinar P, Tempero MA, Collisson EA

Quantitative and Visual Assessments toward Potential Sub-mSv or Ultrafast FDG PET Using High-Sensitivity TOF PET in PET/MRI.

Molecular imaging and biology : MIB : the official publication of the Academy of Molecular Imaging

Behr SC, Bahroos E, Hawkins RA, Nardo L, Ravanfar V, Capbarat EV, Seo Y

Quantification of 89 Zr-Iron oxide nanoparticle biodistribution using PET-MR and ultrashort TE sequences.

Journal of magnetic resonance imaging : JMRI

Jordan CD, Han M, Kondapavulur S, Vera DB, Neumann KD, Moore T, Stillson C, Krug R, Behr S, Seo Y, VanBrocklin HF, Larson PEZ, Wilson M, Martin AJ, Hetts SW

Arteriovenous malformation of the ureter diagnosed by CT urogram.

Urology case reports

Calabrese E, Baghdanian AH, Zagoria RJ, Behr SC

Association between misty mesentery with baseline or new diagnosis of cancer: a matched cohort study.

Clinical imaging

Marcus SG, Candia S, Kohli MD, Mongan J, Zagoria RJ, Behr SC, Sun D, Westphalen AC

Magnetic Particle Imaging for Highly Sensitive, Quantitative, and Safe in Vivo Gut Bleed Detection in a Murine Model.

ACS nano

Yu EY, Chandrasekharan P, Berzon R, Tay ZW, Zhou XY, Khandhar AP, Ferguson RM, Kemp SJ, Zheng B, Goodwill PW, Wendland MF, Krishnan KM, Behr S, Carter J, Conolly SM

From Inguinal Hernias to Spermatic Cord Lipomas: Pearls, Pitfalls, and Mimics of Abdominal and Pelvic Hernias.

Radiographics : a review publication of the Radiological Society of North America, Inc

Cabarrus MC, Yeh BM, Phelps AS, Ou JJ, Behr SC

Optimal MRI sequences for 68Ga-PSMA-11 PET/MRI in evaluation of biochemically recurrent prostate cancer.

EJNMMI research

Lake ST, Greene KL, Westphalen AC, Behr SC, Zagoria R, Small EJ, Carroll PR, Hope TA

Impact of the integration of proton magnetic resonance imaging spectroscopy to PI-RADS 2 for prediction of high grade and high stage prostate cancer.

Radiologia brasileira

Leapman MS, Wang ZJ, Behr SC, Kurhanewicz J, Zagoria RJ, Carroll PR, Westphalen AC

Alliance for clinical trials in oncology (ALLIANCE) trial A021501: preoperative extended chemotherapy vs. chemotherapy plus hypofractionated radiation therapy for borderline resectable adenocarcinoma of the head of the pancreas.

BMC cancer

Katz MHG, Ou FS, Herman JM, Ahmad SA, Wolpin B, Marsh R, Behr S, Shi Q, Chuong M, Schwartz LH, Frankel W, Collisson E, Koay EJ, Hubbard JM, Leenstra JL, Meyerhardt J, O'Reilly E

Real-Time Transferrin-Based PET Detects MYC-Positive Prostate Cancer.

Molecular cancer research : MCR

Aggarwal R, Behr SC, Paris PL, Truillet C, Parker MFL, Huynh LT, Wei J, Hann B, Youngren J, Huang J, Premasekharan G, Ranatunga N, Chang E, Gao KT, Ryan CJ, Small EJ, Evans MJ

Intraperitoneal metastases after transarterial embolization of hepatocellular carcinoma: An observational study.

Abdominal radiology (New York)

Meier JM, Behr SC, Jordan E, Pallav Kolli K, Yeh BM

PET/MR Imaging in Gynecologic Oncology.

Magnetic resonance imaging clinics of North America

Ohliger MA, Hope TA, Chapman JS, Chen LM, Behr SC, Poder L

Incidental Detection of Head and Neck Squamous Cell Carcinoma on 68Ga-PSMA-11 PET/CT.

Clinical nuclear medicine

Lawhn-Heath C, Flavell RR, Glastonbury C, Hope TA, Behr SC

Imaging Hepatocellular Carcinoma With 68Ga-Citrate PET: First Clinical Experience.

Molecular imaging

Mari Aparici C, Behr SC, Seo Y, Kelley RK, Corvera C, Gao KT, Aggarwal R, Evans MJ

Imaging of autoimmune biliary disease.

Abdominal radiology (New York)

Yeh MJ, Kim SY, Jhaveri KS, Behr SC, Seo N, Yeh BM

A Feasibility Study Showing [68Ga]Citrate PET Detects Prostate Cancer.

Molecular imaging and biology

Behr SC, Aggarwal R, Seo Y, Aparici CM, Chang E, Gao KT, Tao DH, Small EJ, Evans MJ

Corrigendum to the inextricable axis of targeted diagnostic imaging and therapy: An immunological natural history approach [Nucl Med Biol 43 (2016) 215-225].

Nuclear medicine and biology

Cope FO, Abbruzzese B, Sanders J, Metz W, Sturms K, Ralph D, Blue M, Zhang J, Bracci P, Bshara W, Behr S, Maurer T, Williams K, Walker J, Beverly A, Blay B, Damughatla A, Larsen M, Mountain C, Neylon E, Parcel K, Raghuraman K, Ricks K, Rose L, Sivakumar A, Streck N, Wang B, Wasco C, Williams A, Schlesinger LS, Azad A, Rajaram MVS, Jarjour W, Young N, Rosol T, McGrath M

Differential Radiographic Appearance of BRAF V600E-Mutant Metastatic Colorectal Cancer in Patients Matched by Primary Tumor Location.

Journal of the National Comprehensive Cancer Network : JNCCN

Atreya CE, Greene C, McWhirter RM, Ikram NS, Allen IE, Van Loon K, Venook AP, Yeh BM, Behr SC

Imaging of flank pain: readdressing state-of-the-art.

Emergency radiology

Jha P, Bentley B, Behr S, Yee J, Zagoria R

Beyond Prostate Adenocarcinoma: Expanding the Differential Diagnosis in Prostate Pathologic Conditions.

Radiographics : a review publication of the Radiological Society of North America, Inc

Li Y, Mongan J, Behr SC, Sud S, Coakley FV, Simko J, Westphalen AC

(18)F-Sodium Fluoride PET-CT Hybrid Imaging of the Lumbar Facet Joints: Tracer Uptake and Degree of Correlation to CT-graded Arthropathy.

World journal of nuclear medicine

Mabray MC, Brus-Ramer M, Behr SC, Pampaloni MH, Majumdar S, Dillon WP, Talbott JF

Rate of observation and inter-observer agreement for LI-RADS major features at CT and MRI in 184 pathology proven hepatocellular carcinomas.

Abdominal radiology (New York)

Ehman EC, Behr SC, Umetsu SE, Fidelman N, Yeh BM, Ferrell LD, Hope TA

Malignancies with Low Fluorodeoxyglucose Uptake at PET/CT: Pitfalls and Prognostic Importance: Resident and Fellow Education Feature.

Radiographics : a review publication of the Radiological Society of North America, Inc

Flavell RR, Naeger DM, Aparici CM, Hawkins RA, Pampaloni MH, Behr SC

The inextricable axis of targeted diagnostic imaging and therapy: An immunological natural history approach.

Nuclear medicine and biology

Cope FO, Abbruzzese B, Sanders J, Metz W, Sturms K, Ralph D, Blue M, Zhang J, Bracci P, Bshara W, Behr S, Maurer T, Williams K, Walker J, Beverly A, Blay B, Damughatla A, Larsen M, Mountain C, Neylon E, Parcel K, Raghuraman K, Ricks K, Rose L, Sivakumar A, Streck N, Wang B, Wasco C, Schlesinger LS, Azad A, Rajaram MVS, Jarjour W, Young N, Rosol T, Williams A, McGrath M

Radiological Evaluation of Bowel Ischemia.

Radiologic clinics of North America

Dhatt HS, Behr SC, Miracle A, Wang ZJ, Yeh BM

Periprocedural Patient Care.

Radiographics : a review publication of the Radiological Society of North America, Inc

Kohi MP, Fidelman N, Behr S, Taylor AG, Kolli K, Conrad M, Hwang G, Weinstein S

Imaging Predictors of Elevated Lung Shunt Fraction in Patients Being Considered for Yttrium-90 Radioembolization.

Journal of vascular and interventional radiology : JVIR

Olorunsola OG, Kohi MP, Behr SC, Kolli PK, Taylor AG, Tong RT, LaBerge JM, Kerlan RK, Fidelman N

Detection of Small Pulmonary Nodules with Ultrashort Echo Time Sequences in Oncology Patients by Using a PET/MR System.

Radiology

Burris NS, Johnson KM, Larson PE, Hope MD, Nagle SK, Behr SC, Hope TA

The combination of axitinib followed by paclitaxel/carboplatin yields extended survival in advanced BRAF wild-type melanoma: results of a clinical/correlative prospective phase II clinical trial.

British journal of cancer

Algazi AP, Cha E, Ortiz-Urda SM, McCalmont T, Bastian BC, Hwang J, Pampaloni MH, Behr S, Chong K, Cortez B, Quiroz A, Coakley F, Liu S, Daud AI

Assessing Biological Response to Bevacizumab Using 18F-Fluoromisonidazole PET/MR Imaging in a Patient with Recurrent Anaplastic Astrocytoma.

Case reports in radiology

Barajas RF, Pampaloni MH, Clarke JL, Seo Y, Savic D, Hawkins RA, Behr SC, Chang SM, Berger M, Dillon WP, Cha S

PET/MR imaging: current and future applications for cardiovascular disease.

Magnetic resonance imaging clinics of North America

Naeger DM, Behr SC

Focal Colonic FDG Activity with PET/CT: Guidelines for Recommendation of Colonoscopy.

World journal of nuclear medicine

Liu T, Behr S, Khan S, Osterhoff R, Aparici CM

Computed tomography of iatrogenic complications of upper gastrointestinal endoscopy, stenting, and intubation.

Radiologic clinics of North America

Valenzuela DM, Behr SC, Coakley FV, Wang ZJ, Webb EM, Yeh BM

The incidence of pulmonary embolism and associated FDG-PET findings in IV contrast-enhanced PET/CT.

Academic radiology

Flavell RR, Behr SC, Brunsing RL, Naeger DM, Pampaloni MH

Diagnosis of Cardiac Metastasis from Endometrial Cancer by F-18 FDG-PET/CT.

Nuclear medicine and molecular imaging

Liu T, Khan S, Behr S, Aparici CM

Imaging of invasive thymoma in the costophrenic recess presenting as thickening of arcuate ligaments of the diaphragm.

Clinical imaging

Coakley FV, Grant MJ, Behr S, Foster BR, Korngold EK, Didier RA

Mesenteric inflammatory veno-occlusive disease: radiographic and histopathologic evaluation of 2 cases.

Abdominal imaging

Miracle AC, Behr SC, Benhamida J, Gill RM, Yeh BC

Triple-negative and non-triple-negative invasive breast cancer: association between MR and fluorine 18 fluorodeoxyglucose PET imaging.

Radiology

Bolouri MS, Elias SG, Wisner DJ, Behr SC, Hawkins RA, Suzuki SA, Banfield KS, Joe BN, Hylton NM

Imaging of müllerian duct anomalies.

Radiographics : a review publication of the Radiological Society of North America, Inc

Behr SC, Courtier JL, Qayyum A

Idiopathic hypertrophic pachymeningitis in six dogs: MRI, CSF and histological findings, treatment and outcome.

The Journal of small animal practice

Roynard P, Behr S, Barone G, Llabrés-Diaz F, Cherubini GB

CT findings in adult celiac disease.

Radiographics : a review publication of the Radiological Society of North America, Inc

Scholz FJ, Afnan J, Behr SC

[18F] Fluorodeoxyglucose positron-emission tomography-CT imaging of carotidynia.

AJNR. American journal of neuroradiology

Amaravadi RR, Behr SC, Kousoubris PD, Raja S

Intramural fat in the duodenum and proximal small intestine in patients with celiac disease.

AJR. American journal of roentgenology

Scholz FJ, Behr SC, Scheirey CD